Apologies Hendrik - I should have left this detail.
Windows 7 Home Premium - Full patched.
When the icon has been clicked on, it runs the splash screen, but never gets any further. I have waited over an hour, I have a very large iTunes Database (140k tracks) and beaTunes takes a little time to load. However after the upgrade to iTunes 10, it didnt start. - IT NOW STARTS, however I cant now get beaTunes to pick up my new songs added to iTunes since I upgraded to iTunes 10
So, it now starts, but it wont pick up my new songs since i upgraded to iTunes 10